Endocrine Abstracts

Prader-Willi is a complex genetic syndrome with characteristic phenotype, obesity, hyperphagia, and endocrine hypothalamic dysfunctions. We present particular features of a case with confirmed Prader Willi syndrome (PWS).Case report: EP, only child of a young non-consanguine couple, was born in 1994 at 34 weeks of amenorrhoea, with a low Apgar score (7) and a weight of 2200 g. She presented important hypotonia in the first 6 weeks of life, needing gavage...

Hormonal treatment (HT) represents the only complete therapy of the consequences of the postmenopausal estrogenic deficiency. Quality of life in postmenopausal women is often compromised. We evaluated the quality of life (appreciated with IQL questionnaire) in 80 postmenopausal women – 40 with intact uterus, treated with natural estrogens associated with progestin, and 40 non-treated women. Group selection (treated/not treated) was made function of the inform consent of t...

Medullary thyroid carcinoma (MTC) is a rare tumoral entity related to parafollicular C cells of the thyroid gland, characterized by peculiar morphological, functional and evolutional features. The aim of this study was to characterize the cases of medullary carcinoma diagnosed in a university hospital in a 5 years interval (January 1999–December 2003) and to evaluate the diagnostic methods. In this time interval, from a total of 171 thyroid malignancy, 12 (7%) were medull...